Anderson Lab -- Dr. Sudhasri Mohanty -- Ohio State University

Sudhasri Mohanty, Ph.D. - Research Scientist
mohanty.5@osu.edu

Education
Training
Fellowships and Awards
Membership
Publications
Abstracts Published, Conference/Symposia Attended
Current Research Projects

Education

1995	PhD, Life Science (Developmental Biology) Jawaharal Nehru University, New Dehli, India
1990	MS, Biochemistry University of Hyderabad, Hyderabad, India.
1987	BS, Cemistry and Biology Ravishankar University, Raipur, India.

Training

2003-present	Research Scientist at Davis Heart & Lung Research Institute at The Ohio State University. Ubiquitous expression of FcRn in human and mouse. Supervisor: Professor Clark. L. Anderson
2001-2003	Post-Graduate Research Associate in Molecular Virology, Immunology and Medical Genetics at The Ohio State University. Roles of viral protein-protein and viral-host protein interactions in Herpes simplex virus replication thus in herpes pathogenesis. Supervisor: Professor Deborah S. Parris
1996-2001	Post-Graduate Researcher at The University of California, San Diego, division of Biology. Studies on targeted protein degradation that is essential for cell type differentiation of Dictyostelium discoideum. Supervisor: Professor Richard A. Firtel
1995 (Fall)	Senior Research Associate at the School of Life Science, Jawaharlal Nehru University, New Delhi, India. Roles of calcium binding protein in stress response. Supervisor: Professor Sudhir K. Sopory
1990-1995	Graduate Student at School of Life Sciences, Jawaharlal Nehru University, New Delhi, India. Thesis title: Studies on the effects of some DNA-acting agents on cellular slime moulds Dictyostelium discoideum. Supervisor: Professor S. Chatterjee
1994 (Summer)	Summer Training at Indian Institute of Science, Bangalore, India. Role of higher and lower calcium levels on cell cycle and cell-type differentiation of Dictyostelium discoideum. Supervisor: Professor V. Nanjundiah

Fellowships and Awards:

1992-1995	University Grant Commission Senior Research Fellow, Government of India
1990-1992	University Grant Commission Junior Research Fellow, Government of India
1989	Selected as a Research Fellow to receive the pre-doctoral fellowship (5 years) from the Center for Scientific and Industrial Research (CSIR), Government of India

Membership

Society for Developmental Biology
Indian Society of Cell Biologists
American Association for Advancement of Science

Publications

Mohanty, S., S. Lee, N. Yadava, M.J. Dealy, R. S. Johnson, R. A. Firtel (2001). Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes Dev. 15(11):1435-48.

Nelson, M. K,. A. Clark, T. Abe, A. Nomura, N. Yadava, C. J. Funair, K. A. Jermyn, S. Mohanty, R. A. Firtel, and J. G. Williams (2000). An F-Box/WD40 repeat-containing protein important for Dictyostelium cell-type proportioning, slug behaviour and culmination. Develop. Biol., 224, 42-59.

Mohanty, S. and R.A. Firtel (2000). Control of spatial patterning and cell-type proportioning in Dictyostelium. In: Seminars in Cell and Developmental Biology (ed. J. Williams), Academic Press, 10, pp. 597-607.

Mohanty, S., K.A. Jermyn, A. Early, T. Kawata, L. Aubry, A. Ceccarelli, P. Schaap, J.G. Williams and R.A. Firtel (1999). Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for chemotaxis. Development 126:3391-3405.

Yasukawa, H., S. Mohanty and R.A. Firtel (1998). Identification and analysis of a gene that is essential for morphogenesis and prespore cell differentiation in Dictyostelium. Development 125:2565-2576.

Clark,A., A. Nomura, S. Mohanty and R.A. Firtel (1997). A ubiquitin-conjugating enzyme is essential for developmental transitions in Dictyostelium. Mol. Biol. Cell 8:1989-2002

Abstracts, Conference/Symposia Attended

Sudhasri Mohanty, Samina Mehnaz, Manzoor A. Wani, John M. Robinson, Derry C. Roopenian, Clark L. Anderson. Widespread expression of the MHC-related receptor for IgG (FcRn). Abstract was accepted for poster presentation in the 12th International Congress of Immunology 2004/4th Annual Conference of FOCIS on July 18-24 at Montreal Canada.

Manzoor A. Wani, Sudhasri Mohanty, and Clark L. Anderson.Genotype of two patients manifesting the phenotype of an FcRn-deficient mouse. Manzoor A. Wani presented a poster on the 12th International Congress of Immunology 2004/4th Annual Conference of FOCIS July 18-24 2004 at Montreal, Canada.

Sudhasri Mohanty, Anson Numura and Richard A. Firtel. Analysis of culA mutant at the Annual International Dictyostelium Conference at Snowbird Utah in August 1997.

Sudhasri Mohanty and S. Chatterjee. XI National Symposia on Developmental Biology 25-17 March 1995, MDU, Rohtak, India. Effects of 5-azacytidine on differentiation of dictyostelium.

Sudhasri Mohanty and S. Chatterjee. X Annual Confererence on Man and Environment, 8-10 March 1995, Goa, India. Effects of arecoline on Dictyostelium development.

Sudhasri Mohanty and S. Chatterjee. International Seminars on Recent Trends in Pharmaceutical Science 18-20 Feb, 1995 Ootacamund, India. Effects of 5-azacytidine on Dictyostelium growth.

Sudhasri Mohanty and S. Chatterjee. XVIII All India Cell Bioligists Conference and Symposia 13-15 Feb 1995, NBRI, Lucknow, India. Effects of arecoline on differentiation of cellular slime moulds, Dictyostelium discoideum.

Sudhasri Mohanty. XVI IUBMB 19-22 September 1994 New Delhi, India. Differentiation of Dictyostelium discoideum is affected by hypomethylating agent 5-azacytidine.

Sudhasri Mohanty and S. Chatterjee. XVII All India Cell Biologists Conference and Symposia 7-9 Jan 1994. Devi Ahilya University, Indore, India. Reversible effects of arecoline on growth of Dictyostelium discoideum.

Sudhasri Mohanty and S. Chatterjee. XXXVIII APPI 27-29 December 1992, School of Life Science, JNU, India. Action of arecoline on differential growth phases and on macromolecular syntheses of Dictyostelium discoium.

Current Research Projects

Currently, I am working on mechanism of FcRn action in human and mice employing biochemical, microscopic and molecular methods. I am the key person overseeing the hybridoma projects involving mAb productions against various epitope of human and mouse FcRn.
I genotype mouse strains including the null strains of FcRn alpha-chain, FcRIIb and HFE and occasionally act as an anesthesiologist for mouse projects.